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. 2021 Nov 4;12:756978. doi: 10.3389/fphar.2021.756978

FIGURE 10.

FIGURE 10

MGQD and FMT attenuated inflammatory response in colonic tissues of mice with DSS-induced colitis. (A) The expression levels of pro-inflammation cytokines IL-17A, IL-21 and anti-inflammation cytokines IL-4 and TGF-β were determined in colon tissue homogenate using ELISA methods among six groups. Results were shown as mean ± SD (n = 5–10). ##p < 0.01, ###p < 0.001, vs control group; *p < 0.05, **p < 0.01, vs DSS group. (B) IL-17A, IL-21, IL-4 and TGF-β cytokines levels in colon tissue homogenate were measured by ELISA between gut microbiota depletion groups. Results were shown as mean ± SD (n = 6–10). #p < 0.05, vs ABX group. (C) IL-17A, IL-21, IL-4 and TGF-β cytokines levels in colon tissue homogenate were measured by ELISA between FMT groups. Results were shown as mean ± SD (n = 5–10). #p < 0.05, ##p < 0.01, vs FMTCON group; *p < 0.05, vs FMTDSS group. NS means no statistical significance.