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. 2021 Nov 4;12:756978. doi: 10.3389/fphar.2021.756978

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Copyright © 2021 Wang, Zhang, Xu, Ma, Lu, Ma, Liu, Wang and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MGQD traetment regulated the proportion of Treg cells and Th17 cells in splenocytes and mesenteric lymph nodes (MLNs) in UC mice. (A) Effect of MGQD on the proportion of CD4⁺CD25 + Foxp3+ (Treg) cells in the spleen and MLNs of mice with colitis were analyzed by flow cytometry. (B) Effect of MGQD on the proportion of CD4+IL-17A+ (Th17) cells in the spleen and MLNs of mice with colitis. (C) Quantitative analysis of Treg and Th17 cells in splenocytes and MLNs. Data were expressed as mean ± SD (n = 3–5). ##p < 0.01, ###p < 0.001, vs control group; *p < 0.05, **p < 0.01, vs DSS group.