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. 2021 Nov 18;16(11):e0258704. doi: 10.1371/journal.pone.0258704

Table 3. Adenovirus vector vaccine effectiveness in the chronically ill aged 16–69 years adjusted for age group, sex, presence of medical conditions and residence in Helsinki-Uusimaa.

Laboratory-confirmed SARS-CoV-2 infection Covid-19 hospitalisation
Cases, n Cumulative riska Vaccine effectivenes, % Cases, n Cumulative riska Vaccine effectivenessb, %
Not vaccinated 5280 859 Reference 528 90 Reference
First dose
21–27 DSV 51 238 24 (-1 to 42) 4 42 67 (10–88)
28–34 DSV 29 129 48 (25–64) 1 3 91 (33–99)
35–41 DSV 29 184 37 (8–56) 6 37 36 (-45 to 72)
42+ DSV 78 106 50 (37–61) 15 21 58 (26–76)
Second dose
7+ DSV 0 0 Not estimated 0 0 Not estimated

a Cumulative risk at the end of the study multiplied by 10000;

b Point estimate and 95% confidence interval; DSV, days since vaccination.