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. Author manuscript; available in PMC: 2021 Nov 18.
Published in final edited form as: Curr Rheumatol Rep. 2021 Jan 29;23(2):12. doi: 10.1007/s11926-020-00978-5

Fig. 1.

Fig. 1

T cell subsets involved in promoting autoantibody-producing plasma cells through aberrant T-B interaction. T follicular helper (Tfh) promotes germinal center B cells (GCB) affinity maturation and class switch in a contact-dependent manner. Other non-canonical T cells subsets include extrafollicular T cells, circulatory Tfh cell, peripheral helper (Tph) cells, and Tfh-like cells residing in damaged organ