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. Author manuscript; available in PMC: 2021 Nov 18.
Published in final edited form as: Growth Factors. 2020 Jun 4;38(2):75–93. doi: 10.1080/08977194.2020.1767612

Table 2:

Vessel morphological parameters (volume, mean diameter, number, separation and connectivity) assessed from sham and ischemic WT or Fgf2−/− 3-D micro-CT angiograms after vascular segmentation. HLI (hindlimb ischemia)

Volume (%) P Diameter (mm) P Number (1/mm) P Separation (mm) P Connectivity (1/mm) P
WT Calf Sham 0.91 ± 0.05 .02 0.08 ± 0.01 .09 0.13 ± 0.02 .03 8.31 ± 0.93 .03 19.39 ± 0.93 0.28
HLI 1.34 ± 0.12* 0.06 ± 0.01 0.22 ± 0.03* 4.93 ± 0.77* 20.62 ± 1.36
Fgf2−/− Calf Sham 0.91 ± 0.13 .03 0.07 ± 0.01 .25 0.14 ± 0.02 .01 7.87 ± 1.42 .01 18.88 ± 1.58 0.04
HLI 1.44 ± 0.30* 0.06 ± 0.003 0.22 ± 0.04* 4.74 ± 0.89* 20.59 ± 1.74*
WT Thigh Sham 0.54 ± 0.06 .12 0.11 ± 0.01 .04 0.05 ± 0.01 .03 21.73 ± 3.44 .02 26.19 ± 3.37 0.06
HLI 0.71 ± 0.10 0.08 ± 0.01* 0.09 ± 0.01* 11.68 ± 1.96* 23.88 ± 2.41
Fgf2−/− Thigh Sham 0.58 ± 0.09 .09 0.09 ± 0.01 .16 0.07 ± 0.02 .01 16.73 ± 4.12 .02 21.71 ± 0.61 0.46
HLI 0.88 ± 0.26 0.06 ± 0.01 0.13 ± 0.03* 8.88 ± 1.70* 23.90 ± 2.18
*

p < 0.05 vs Sham cohort