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. 2021 Nov 19;19:303. doi: 10.1186/s12916-021-02187-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Overall SARS-CoV-2-adjusted seroprevalence over time superimposed on Malawi national PCR-confirmed COVID-19 cases. Black dots (together with 95% CI) are estimated seroprevalence at each time point (month), adjusted for assay sensitivity and specificity. The histograms represent confirmed national COVID-19 cases per month, including asymptomatic and symptomatic cases. The vertical dotted line defines the transition from 2020 to 2021. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; COVID-19, coronavirus disease 2019; Ab+, positive for the detection of anti-SARS-CoV-2 receptor-binding domain (RBD) antibody