(g).
| HNF4A | Adj OR (95% CI) | p value | Adj OR (95% CI) | p value | Adj OR (95% CI) | p value |
|---|---|---|---|---|---|---|
| rs1800961 | ||||||
| All patients† | Adjusted OR† | Adjusted OR† | Adjusted OR† | |||
| CC | Ref | Ref | Ref | |||
| CT | 0.90 (0.45–1.82) | 0.78 | 1.96 (1.01–3.80) | 0.04 | 3.75 (1.64–8.60) | 0.002 ∗ |
| TT | 1 | — | 1 | — | 1 | — |
| X 2 | ||||||
| Genotype | NA | NA | NA | |||
| Allele | 0.114 | 4.592 | 6 | |||
| Male‡ | Adjusted OR‡ | Adjusted OR‡ | Adjusted OR‡ | |||
| CC | Ref | Ref | Ref | |||
| CT | 1.50 (0.46–4.92) | 0.49 | 1.48 (0.52–4.21) | 0.45 | 6.08 (1.25–29.48) | 0.02 |
| TT | — | — | — | — | — | — |
| Female‡ | ||||||
| CC | Ref | Ref | Ref | |||
| CT | 0.67 (0.27–1.66) | 0.39 | 2.36 (1.01–5.56) | 0.04 | 3.23 (1.22–8.58) | 0.01 |
| TT | 1 | — | 1 | — | 1 | — |
| Never smoking¶ | Adjusted OR¶ | Adjusted OR¶ | Adjusted OR¶ | |||
| CC | Ref | Ref | Ref | |||
| CT | 0.97 (0.43–2.19) | 0.95 | 1.84 (0.77–4.35) | 0.16 | 2.96 (1.16–7.53) | 0.02 |
| TT | 1 | — | — | — | 1 | — |
| Ever smoking†¶ | ||||||
| CC | Ref | Ref | Ref | |||
| CT | 0.72 (0.18–2.83) | 0.64 | 2.14 (0.76–6.01) | 0.14 | 6.23 (0.74–52.09) | 0.09 |
| TT | 1 | — | 1 | — | 1 | — |
Bold font indicates p < 0.05; ∗indicates statistical significance after Bonferroni correction (p < 0.003). †OR with 95% CI were estimated by multiple logistic regression models after controlling for age, sex, and smoking. ‡OR with 95% CI were estimated by multiple logistic regression models after controlling for age and smoking. ¶OR with 95% CI were estimated by multiple logistic regression models after controlling for age and sex. ¥OR with 95% CI were estimated by multiple logistic regression models after controlling for age, considering only females who never smoked. Abbreviations: OR: odds ratio; CI: confidence interval.