Figure 4.

Plasma TAGs correlate with islet lipid signaling and oxidative phosphorylation pathways. A. Genes of the “lipid signaling” term of the black module and their Spearman correlation coefficients with plasma TAGs (shown only for correlations with adjusted p-values <0.05 and |rho|≥0.4). These genes encoded enzymes contributing to the phospholipids (blue), phosphatidylinositol (green), and sphingolipids (orange) metabolic pathways. B. Scheme of the oxidative phosphorylation pathway with, in blue boxes, the genes of the “oxidative phosphorylation” term of the blue and cyan modules. C. Spearman correlation coefficients between expression of the “oxidative phosphorylation” genes and plasma TAGs.