Figure 2.

Regulatory and effector CD4+ T cells from the PLNs and spleen of TLR3^+/- and TLR3^+/+ mice post-CB4 infection. (A) Regulatory T cells (Foxp3⁺ CD4⁺) and (B, C) effector T cells (CD44^hiCD62^lowCD4⁺ and IFNγ-producing CD4⁺) were isolated from the pancreatic lymph nodes (PLNs) and spleens of TLR3+/+ (n = 5) and TLR3+/- mice (n = 5) at day 7 post CB4-infection and were stained with classical activation and maturation marker antibodies for FACS analysis. Results are shown as mean ± SEM of a representative from three independent experiments. *p < 0.05.