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. 2021 Nov 5;12:747580. doi: 10.3389/fneur.2021.747580

Table 3.

Match of predicted values of individual, multistructural and multimodal study metrics with actual outcomes (Engel class 1 vs. Engel class ≥ 2).

Criteria (i) Vol Ratio (ii) FLAIR (iii) MSA (iv) PET (v) MMM (vii) DTI Uncertainty (vii) DTI Connectivity (viii) fMRI Connectivity
Engel 1 13/17 = 0.76 9/13 = 0.69 15/17 = 0.88 10/12 = 0.83 14/17 = 0.82 7/10 = 0.70 5/9 = 0.56 2/2 = 1
Engel ≥2 4/7 = 0.57 3/7 = 0.43 3/7 = 0.43 2/3 = 0.67 4/7 = 0.57 0/3 = 0.00 1/3 = 0.33 -
Engel class 1 Outcomes Engel class ≥ 2 Outcomes
R \ M L&UL R&UR U L&UL R&UR U
Hippocampal Volume L 6 1 0 2 2 0
R 2 7 1 1 2 0
FLAIR L 4 1 1 2 1 1
R 1 5 1 1 1 1
MSA L 5 2 0 1 2 0
R 0 8 1 1 2 0
PET L 4 0 0 1 0 0
R 1 6 1 0 1 1
MMM L 5 1 1 2 1 1
R 0 9 1 0 2 1
DTI (u) L 5 0 0 0 0 1
R 0 1 4 1 0 1
DTI (c) L 2 0 1 0 0 1
R 1 3 2 0 0 2

Note: each row in the upper display shows the number of cases predicted in each category leading to the identified outcome so that for Engel class ≥ 2, the number of wrong-side predictions are provided. Comparative tables (Engel class 1 vs. Engel class ≥ 2) show outcomes achieved by resection (R) following standard clinical protocol decision-making (left vs. right) and by model prediction (M) for each attribute, indicating absolute or partial determinacy for the epileptogenic side (L & UL vs. R & UR).