Table 1.

Anthropometric, metabolic and hormonal differences between obesity, lipodystrophies and insulin receptoropathy

Characteristics	Obesity $\uparrow$ (with Metabolic Syndrome)	Lipodystrophies	Insulin receptoropathy
BMI	$\uparrow$	$\downarrow$	$\leftrightarrow$
Body fat %	$\uparrow$	$\downarrow \downarrow \downarrow$	$\leftrightarrow$
Waist (cm)	$\uparrow$	$\leftrightarrow \downarrow$	$\leftrightarrow$
Hip (cm)	Relative $\downarrow$	$\downarrow$$\downarrow$	$\leftrightarrow$
Waist/hip ratio	$\uparrow \uparrow$	$\uparrow \uparrow$	$\leftrightarrow$
Insulin resistance	$\uparrow$	$\uparrow \uparrow$	$\uparrow \uparrow \uparrow$
Triglycerides	$\uparrow$	$\uparrow \uparrow$	$\leftrightarrow$
HDL cholesterol	$\downarrow$	$\downarrow$	$\leftrightarrow$
Leptin	$\uparrow \uparrow$	$\downarrow$$\downarrow$$\downarrow$/$\downarrow$	$\leftrightarrow$
NAFLD	$\uparrow$	$\uparrow \uparrow$	Absent
PCOS	$\uparrow$	$\uparrow \uparrow$	$\uparrow \uparrow$
Atherosclerosis	$\uparrow$	$\uparrow \uparrow$	Unknown

Modified from [63]

NAFLD non-alcoholic fatty liver disease, PCOS polycystic ovary syndrome