Fig. 2. Scope of the mechanochemical synthesis of organomagnesium nucleophiles and their nucleophilic addition to aldehydes and ketones in a ball mill.

A stainless-steel milling jar (5 mL) and stainless-steel ball (diameter: 10 mm) were used. Isolated yields are reported as percentages. Proton NMR integrated yields are shown in parentheses. For details, see the Supplementary Information.