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. 2021 Nov 18;12:6738. doi: 10.1038/s41467-021-27099-6

Fig. 4. Re-expression of MIR1307 rescues chemotherapy-induced cytotoxicity and DNA damage in MIR1307KO cells.

Fig. 4

A Cells were treated with DMSO or FOI chemotherapy for 48 h and assessed for cell viability by CellTiter-Blue. Bars represent the mean and SD of six replicates. Values from two-sided t-test are reported. B Cells were treated for 48 h and COMET assay performed afterwards. Representative images are shown (magnification/scale 20×; magnification bar indicates 50 μm). C Quantification plots of the COMET assay are shown with median and interquartile ranges. A median of 90 cells (across three replicates) was assessed for each sample. Values from two-sided t-test are reported.