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. 2021 Nov 18;4:1306. doi: 10.1038/s42003-021-02837-0

Fig. 2. O304 improves cardiac function in aging mice.

Fig. 2

In all diagrams mice were fed CD or O304-0.5 from 6 months of age. a–f Stroke volume (a), cardiac output (b), end-diastolic volume (c), end-systolic volume (d), ejection fraction (e), and heart rate (f), in mice fed CD (n = 7) or O304-0.5 (n = 6) for 7 weeks. g–l Stroke volume (g), cardiac output (h), end-diastolic volume (i), end-systolic volume (j), ejection fraction (k), and heart rate (l), in mice fed CD (n = 8) or O304-0.5 (n = 8) for 6 and 12 months (mo). Data are presented as mean ± s.d. Student’s t-test between CD and O304-0.5 at respective time point. *P ≤ 0.05, **P ≤ 0.01, and ***P ≤ 0.001.