Skip to main content
. 2021 Nov 18;4:1306. doi: 10.1038/s42003-021-02837-0

Fig. 4. O304 improves cardiac function in aged mice.

Fig. 4

In all diagrams mice were fed CD or O304-0.5 for 6 months with diet start at 12 months of age. a–e, h Stroke volume (a), cardiac output (b), end-diastolic volume (c), ejection fraction (d), heart rate (sedated mice) (e), and end-systolic volume (h), in mice fed CD (n = 7) or O304-0.5 (n = 9) before start and at 1 and 6 months (mo) of diet. f, g Heart rate (non-sedated mice) (f), and endurance test (g), in mice fed CD (n = 8) or O304-0.5 (n = 8) at 6 months (mo) of diet. i Blood pressure in mice fed CD (n = 8) and O304-0.5 (n = 8) at 6 months (mo) of diet. Data are presented as mean ± s.d. Student´s t-test between CD and O304-0.5 diet groups at respective time point. *P ≤ 0.05, **P ≤ 0.01, and ***P ≤ 0.001.