Fig. 4.

STEM effects on grip strength, muscle mass, and collagen content after hindlimb unloading: panels represent A grip strength of PBS- and STEM-treated mice at baseline (1 day prior to treatment), repeated at day 7 of HU (hindlimb unloading), and day 13 of HU (1 day prior to tissue harvest). B Soleus muscle mass (mg/g); C soleus muscle cross-sectional area (CSA) displayed in um²; and D soleus muscle BCHP, COLIV, and BCHP/COLIV ratio in PBS- and STEM-treated mice after 14 days of HU. Representative immunohistochemistry images are depicted next to panel. N = 5 mice in each group. Results are mean with standard error of the mean. Two-way ANOVA-repeated measures used for panel A. T-test between PBS and STEM (B–D). *** = all PBS groups different to each other. * = different to PBS