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. 2021 Nov 18;12:6689. doi: 10.1038/s41467-021-26936-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The number of a genomic (detected by RNA-seq/WGS) and b proteomic (detected by LC-MS/MS) tumor-specific events are shown for 46 medulloblastoma tumors. The type of tumor-specific genomic events is indicated: SNV/indels (purple), junctions (blue), and gene fusions (orange). The number of identified tumor-specific peptides ranged from 1 to 43 peptides per tumor with a mean of 9 peptides per tumor. c Tile plot depicting the number of tumor-specific peptides identified in medulloblastoma tumors. Black tiles indicate unannotated peptides identified in healthy cerebellum or normal tissues from GTEX. SNVs, fusions, and junctions are shown in purple, orange, and blue respectively. Each gray tile represents a peptide, although some peptides are found in multiple tumors, the vast majority are tumor-specific. Source data are provided as a Source Data file.