TABLE 4.
Top 30 GPCRs (see the full GPCR list in Supplementary Table 1).
| Gene symbol | Gene name | Class | Mean (TPM) | S.E.M. | Rank |
| Adgrg1 | Adhesion G protein-coupled receptor G1 | Adhesion G protein-coupled receptors, subfamily G | 93.06 | 6.39 | 1,343 |
| Gprc5c | G protein-coupled receptor, family C, group 5, member C | G protein-coupled receptors, Class C orphans | 87.39 | 2.36 | 1,443 |
| Gprc5a | G protein-coupled receptor, family C, group 5, member A | G protein-coupled receptors, Class C orphans | 74.50 | 2.49 | 1,719 |
| F2r | Coagulation factor II (thrombin) receptor | F2R receptors | 43.62 | 1.65 | 2,992 |
| Tpra1 | Transmembrane protein, adipocyte associated 1 | 7TM orphan receptors | 34.63 | 0.79 | 3,641 |
| Adgrl2 | Adhesion G protein-coupled receptor L2 | Adhesion G protein-coupled receptors, subfamily L | 29.26 | 1.34 | 4,220 |
| F2rl1 | Coagulation factor II (thrombin) receptor-like 1 | F2R receptors | 23.20 | 1.07 | 5,055 |
| Adgre5 | Adhesion G protein-coupled receptor E5 | Adhesion G protein-coupled receptors, subfamily E | 23.00 | 0.83 | 5,088 |
| Smo | Smoothened, frizzled class receptor | G protein-coupled receptors, Class F frizzled | 22.86 | 0.74 | 5,106 |
| Gpr137 | G protein-coupled receptor 137 | 7TM orphan receptors | 21.52 | 0.75 | 5,291 |
| Gpr108 | G protein-coupled receptor 108 | 7TM orphan receptors | 21.06 | 0.88 | 5,368 |
| Fzd6 | Frizzled class receptor 6 | G protein-coupled receptors, Class F frizzled | 20.98 | 0.82 | 5,385 |
| Gpr107 | G protein-coupled receptor 107 | 7TM orphan receptors | 19.89 | 1.06 | 5,600 |
| Gabbr1 | Gamma-aminobutyric acid (GABA) B receptor, 1 | Gamma-aminobutyric acid type B receptor subunits | 16.97 | 1.36 | 6,202 |
| Adora1 | Adenosine A1 receptor | Adenosine receptors | 15.32 | 0.64 | 6,594 |
| Lgr4 | Leucine-rich repeat-containing G protein-coupled receptor 4 | G protein-coupled receptors, Class A orphans | 13.87 | 0.54 | 6,910 |
| Adgra3 | Adhesion G protein-coupled receptor A3 | Adhesion G protein-coupled receptors, subfamily A | 12.81 | 0.97 | 7,206 |
| Ptger4 | Prostaglandin E receptor 4 (subtype EP4) | Prostaglandin receptors | 11.67 | 0.43 | 7,534 |
| Gpr161 | G protein-coupled receptor 161 | G protein-coupled receptors, Class A orphans | 11.52 | 0.34 | 7,593 |
| Gpr19 | G protein-coupled receptor 19 | G protein-coupled receptors, Class A orphans | 11.31 | 0.50 | 7,664 |
| Celsr2 | Cadherin, EGF LAG seven-pass G-type receptor 2 | Adhesion G protein-coupled receptors, subfamily C | 11.29 | 0.89 | 7,667 |
| Adgrg6 | Adhesion G protein-coupled receptor G6 | Adhesion G protein-coupled receptors, subfamily G | 10.66 | 0.69 | 7,856 |
| Gpr160 | G protein-coupled receptor 160 | G protein-coupled receptors, Class A orphans | 10.30 | 0.50 | 7,948 |
| Fzd1 | Frizzled class receptor 1 | G protein-coupled receptors, Class F frizzled | 9.19 | 0.31 | 8,316 |
| Fzd7 | Frizzled class receptor 7 | G protein-coupled receptors, Class F frizzled | 7.65 | 0.27 | 8,887 |
| P2ry2 | Purinergic receptor P2Y, G-protein coupled 2 | P2Y receptors | 6.67 | 0.17 | 9,291 |
| Gpr39 | G protein-coupled receptor 39 | G protein-coupled receptors, Class A orphans | 5.72 | 0.20 | 9,673 |
| Pitpnm3 | PITPNM family member 3 | Atypical chemokine receptors | 5.70 | 0.40 | 9,679 |
| Lgr6 | Leucine-rich repeat-containing G protein-coupled receptor 6 | G protein-coupled receptors, Class A orphans | 5.35 | 0.33 | 9,813 |
| Gpr146 | G protein-coupled receptor 146 | G protein-coupled receptors, Class A orphans | 5.16 | 0.25 | 9,903 |