Table 2.

Significant clusters for psychophysiological interaction analyses using the Alcohol > Beverage contrast, IBUD<PLAC, Ventral Striatum seed. Z-statistic maps were thresholded using cluster-corrected statistics with a height-threshold of Z > 2.3 and cluster-forming threshold of p < 0.05. All coordinates are in MNI space.

Brain Region	Cluster Voxels	Max Z-statistic	x	y	z
Placebo > Ibudilast – PPI during Alc>Bev; VS Seed
L Orbitofrontal Cortex	9599	4.13	−46	18	−16
Bilateral Anterior Cingulate		3.8	0	14	18
R Medial Frontal Cortex		3.68	2	46	−12
L Superior Frontal Gyrus		3.65	−6	46	32