Table 1.
Baseline characteristics for patients with HCC.
| Overall | UEBMI | URRBMI | P | |
|---|---|---|---|---|
| (N = 2,068) | (N = 1,498) | (N = 570) | ||
| Demographic characteristics | ||||
| Age [Mean (SD)] | 60.7 (12.6) | 60.6 (12.9) | 60.9 (11.6) | 0.667 |
| Female [N (%)] | 634 (30.7%) | 476 (31.8%) | 158 (27.7%) | 0.074 |
| Comorbidities and complications [N (%)] | ||||
| CCI score [Mean (SD)] | 4.44 (2.16) | 4.69 (2.23) | 3.78 (1.81) | <0.001 |
| Comorbidities related to the liver | ||||
| Hepatitis | 916 (44.3%) | 660 (44.1%) | 256 (44.9%) | 0.727 |
| HBV | 741 (35.8%) | 525 (35.0%) | 216 (37.9%) | 0.227 |
| HCV | 82 (4.0%) | 69 (4.6%) | 13 (2.3%) | 0.015 |
| Cirrhosis of the liver | 939 (45.4%) | 663 (44.3%) | 276 (48.4%) | 0.089 |
| Compensated cirrhosis | 490 (23.7%) | 365 (24.4%) | 125 (21.9%) | 0.244 |
| Decompensated cirrhosis† | 449 (21.7%) | 298 (19.9%) | 151 (26.5%) | 0.001 |
| Hepatic failure | 266 (12.9%) | 176 (11.7%) | 90 (15.8%) | 0.014 |
| Fatty liver disease | 92 (4.4%) | 79 (5.3%) | 13 (2.3%) | 0.003 |
| Alcoholic liver disease‡ | 52 (2.5%) | 42 (2.8%) | 10 (1.8%) | 0.173 |
| Ascites | 366 (17.7%) | 232 (15.5%) | 134 (23.5%) | <0.001 |
| Hepatic encephalopathy | 202 (9.8%) | 151 (10.1%) | 51 (8.9%) | 0.438 |
| Jaundice | 137 (6.6%) | 104 (6.9%) | 33 (5.8%) | 0.346 |
| Portal hypertension | 82 (4.0%) | 57 (3.8%) | 25 (4.4%) | 0.545 |
| Esophageal variceal bleeding | 54 (2.6%) | 38 (2.5%) | 16 (2.8%) | 0.731 |
| Primary peritonitis | 52 (2.5%) | 37 (2.5%) | 15 (2.6%) | 0.834 |
| Hepatorenal syndrome | 35 (1.7%) | 31 (2.1%) | 4 (0.7%) | 0.031 |
| All-cause resource utilization and costs | ||||
| Total cost [Mean(SD), CNY] | 7,505 (16,870) | 8,940 (17,501) | 3,733 (14, 435) | <0.001 |
| Any hospitalizations [N (%)] | 428 (20.7%) | 314 (21.0%) | 114 (20.0%) | 0.630 |
| ALOS per hospitalization [Mean(SD)] | 12.9 (10.5) | 14.0 (11.4) | 9.9 (6.6) | <0.001 |
| Any outpatient visits [N (%)] | 1,578 (76.3%) | 1,424 (95.1%) | 154 (27.0%) | <0.001 |
CCI score, Charlson Comorbidity Index score; HBV, hepatitis B virus; HCV, hepatitis C virus; CNY, Chinese yuan (year-2017 1 USD = 6.77 CNY); ALOS, Average length of stay.
Patients with liver cirrhosis who had the following symptoms were defined as decompensated liver cirrhosis: ascites; esophageal variceal bleeding; hepatorenal syndrome; portal hypertension; hepatic encephalopathy and jaundice; hepatic encephalopathy and primary peritonitis; jaundice and primary peritonitis.
Including alcoholic liver cirrhosis, alcoholic hepatitis, alcoholic fatty liver disease and alcoholic liver failure; hepatitis, liver cirrhosis, fatty liver disease and liver failure in this table only included non-alcoholic disease. Bold values means P < 0.05.