TABLE 4.
Report of the univariate and multivariate regression analysis for the prediction of TAC concentrations in PBMC. All the statistics have been reported in APA format.
| Intra-PBMC TAC concentration | Univariate analysis | |||||
|---|---|---|---|---|---|---|
| Age | Weight-adjusted dose | Hematocrit | Albumins | Gender | ||
| F (d.f.; res.) | - | 41.5 (1; 26) | 18.3 (1; 26) | 5.9 (1; 26) | 7.1 (1; 26) | |
| Unstand. B coef. | - | 201.2 | −3.2 | −33.3 | 17.9 | |
| p value | - | <0.001 | <0.001 | 0.010 | 0.013 | |
| Intercept | - | 8.4 | 149.3 | 169.9 | 12.3 | |
| R2 | - | 0.624 | 0.432 | 0.190 | 0.274 | |
| Intra-PBMC TAC concentration adjusted by dose/weight ratio (C/D/Kg) | Univariate analysis | |||||
| Age | Weight-adjusted dose | Hematocrit | Albumins | Gender | ||
| F (d.f.; res.) | 6.8 (1; 26) | - | - | - | - | |
| Unstand. B coef. | 38.0 | - | - | - | - | |
| p value | 0.015 | - | - | - | - | |
| Intercept | −109.1 | - | - | - | - | |
| R 2 | 0.215 | - | - | - | - | |
| Intra-PBMC TAC concentration | Multivariate analysis (final model) | |||||
| Age | Weight-adjusted dose | |||||
| F (d.f.; res.) | 25.7 (2; 25) | |||||
| Unstand. B coef. | −1.0 | 216.0 | ||||
| p value | 0.049 | <0.001 | ||||
| Intercept | −1.65 | |||||
| R 2 | 0.681 | |||||