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. 2021 Nov 5;12:769425. doi: 10.3389/fimmu.2021.769425

Figure 8.

Figure 8

The underlying mechanism and pathways in the risk score model. (A) Correlation between risk score and the steps of the cancer immunity cycle. (B) Correlation between risk score and the enrichment score of immunotherapy-predicted pathways. (C) PAAD-specific cancer driver genes expressed in groups with different m6A gene clusters, immune infiltration, risk score, TIDE score, and survival status. The statistics results presented in the picture was analyzed between high and low risk subgroups. (D) The most altered genes frequency in six m6A genes altered and unaltered group. (E) GSEA showed multiple cancer-related signaling pathway are positively enriched in high-risk group. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.