Table 2.

Haematology, blood biochemistry and necropsy parameters in the tolerance study

	mg 3‐NOP/kg feed DM
	Control	90.2 (× 0.8)	106.8 (× 1)	220.4 (× 2)
Monocytes d5 (×109/L)	0.54	0.48	0.46	0.43*
Monocytes d56 (×109/L)	0.36	0.31	0.30■	0.30■
Red blood cells (×1012/L)	6.78	6.52*	6.39*	6.42*
Haematocrit (%)	29	28*	28*	27*
Mean corpuscular haemoglobin (pg)	16.2	16.5*	16.5■	16
Haemoglobin d56 (g/L)	112	110	109	103*
Prothrombin time (s)	28.9	27.3*	27.7■	27.0*
Fibrinogen (g/L)	0.85	0.88	0.93	1.00*
ALT (U/L)	30	27*	27*	24*
LDH d56 (U/L)	1267	1249	1245	1034*
Total cholesterol (mmol/L)	4.50	4.26■	4.18*	4.18*
Triglycerides (mmol/L)	0.143	0.126■	0.130	0.124*
Albumin (g/L)	36	36	36	35*
Ca (mmol/L)	2.40	2.46■	2.47*	2.40
Amylase (U/L)	34	34	34	31*
Ovary absolute size (g)	35.2	31.9	29.7	25.8*
Ovary relative size (g per kg final bw)	0.050	0.048	0.040	0.039■

3‐NOP: 3‐nitrooxypropanol; DM: dry matter; ALT: alanine transaminase; LDH: lactate dehydrogenase; bw: body weight.

^■p < 0.10, *p < 0.05, level of significance of the difference compared with the control group.