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. 2021 Nov 5;11:755212. doi: 10.3389/fonc.2021.755212

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Copyright © 2021 Jiang, Meng, Bao, Wang, Gong, Gan, Wang, Bao, Wu, Lu, Liu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Crosstalk between cancer and immune cells. (A) The t-SNE plot shows that 29,799 cells were divided into 35 clusters, among which T cell accounts for the largest cluster. (B) Pyroptosis- related genes expressed in the 10 cell clusters. (C) Cell–cell interaction in cell clusters as analyzed by “CellChat.” (D) Cell–cell interaction in cell clusters as analyzed by “cellphonedb.” (E) Connection probability of main signaling pathways in cell clusters as analyzed by “CellChat.” (F) TNF signaling pathways between T cells and other cells. (G) Connection probability of main signaling pathways in cell clusters as analyzed by “cellphonedb.” (H) Correlation of the communication ratio between cell clusters.