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. 2021 Nov 19;184(26):6229–6242.e18. doi: 10.1016/j.cell.2021.11.026
Parameter Definition Default value
φ Probability of cross-protection given infection with either strain 0 or 0.6
ω Maximum vaccine efficacy (probability of protection against perfect antigenic match) 0.95
α1 Probability vaccine fails to elicit immunity against strain 1 (due to antigenic mismatch) 0
α2 Probability vaccine fails to elicit immunity against strain 2 (due to antigenic mismatch) 1φ