Table. Selected Characteristics of Data Set 1: 2088 Registered US Clinical Trials With Posted Informed Consent Forms on ClinicalTrials.gov.
| Characteristic | Records, No (%) |
|---|---|
| Trial attribute | |
| Key funder typea | |
| NIH | 697 (33.4) |
| Other federal agency | 148 (7.1) |
| Industry | 257 (12.3) |
| Other (eg, foundation) | 986 (47.2) |
| Current overall recruitment status | |
| Active, not recruiting | 204 (9.8) |
| Completed | 1271 (60.9) |
| Enrolling by invitation | 26 (1.2) |
| Not yet recruiting | 18 (0.9) |
| Recruiting | 279 (13.4) |
| Suspended | 9 (0.4) |
| Terminated | 249 (11.9) |
| Unknown status | 27 (1.3) |
| Withdrawn | 5 (0.2) |
| Enrollment (anticipated or actual), No. of participants | |
| 0-50 | 1050 (50.3) |
| 51-100 | 399 (19.1) |
| 101-500 | 509 (24.4) |
| >500 | 130 (6.2) |
| Intervention type, at least 1 of following | |
| Behavioral | 537 (25.7) |
| Device, diagnostic, or radiation | 468 (22.4) |
| Medical procedure | 130 (6.2) |
| Dietary supplement, combination, other | 457 (21.9) |
| Drug, biologic, or genetic | 976 (46.7) |
| Not applicable | 56 (5.7) |
| Early phase 1 or phase 1 | 138 (14.1) |
| Phase 1/2 or phase 2 | 481 (49.3) |
| Phase 2/3 or phase 3 | 124 (12.7) |
| Phase 4 | 177 (18.1) |
| Top 5 conditions, at least 1 of the following | |
| Obesity | 47 (2.3) |
| Depression | 45 (2.2) |
| Prostate cancer | 39 (1.9) |
| Breast cancer | 33 (1.6) |
| Stroke | 31 (1.5) |
| Study design | |
| Not provided | 3 (0.1) |
| 1 Arm | 563 (27.0) |
| >1 Arm | 1522 (72.9) |
| Randomized allocation | 1324 (87.0) |
| Lead sponsor | |
| Industry (85 sponsors) | 116 (5.6) |
| No. of trials per sponsor | |
| Mean (range) | 1.4 (1-7) |
| Median (IQR) | 1 (1-1) |
| Nonindustry (542 sponsors) | 1972 (94.4) |
| No. of trials per sponsor | |
| Mean (range) | 3.6 (1-132) |
| Median (IQR) | 1 (1-3) |
Abbreviation: NIH, National Institutes of Health.
a
Key funder types were categorized as “NIH” if at least 1 NIH institute or center was listed as the lead sponsor or collaborator, as “other federal agency” if not classified as NIH and at least 1 federal agency (other than NIH) or department was listed as the lead sponsor or collaborator, as “industry” if not classified as either NIH or other federal agency and at least 1 company was listed as the lead sponsor or collaborator, and as “other” for all remaining records (eg, foundation funding).