Table 1:

Unadjusted comparisons of demographic characteristics, categories of spinal segmental level of motor function, and the age at last visit recorded in the NSBPR between fetal surgery patients (n=298) and postnatal surgery patients matched for date of birth (±3mo) (n=648), assessed when patients in both cohorts were at least 12 months of age

Covariate	Fetal surgery, n (%)	Postnatal surgery, n (%)	IRR (95% CI); p
Male sex	147/298 (49)	321/648 (50)	1.00 (0.76–1.32); 0.99
Female sex	151/298 (51)	327/648 (50)
Non-Hispanic white	236/285 (83)	404/631 (64)	3.06 (2.07–4.54); <0.01
Non-Hispanic black	10/285 (4)	75/631 (12)	0.30 (0.15–0.58); <0.01
Hispanic	34/287 (12)	136/641 (21)	0.41 (0.26–0.66); <0.01
Private insurance	218/298 (73)	335/648 (52)	2.76 (2.00–3.81); <0.01
Sacral level	102 (34)	163 (25)	Reference
Low lumbar level	81 (27)	151 (23)	0.94 (0.64–1.37); 0.75
Mid-lumbar level	79 (27)	176 (27)	0.75 (0.50–1.11); 0.15
High lumbar level	16 (5)	87 (13)	0.30 (0.16–0.55); <0.01
Thoracic level	20 (7)	71 (11)	0.47 (0.26–0.84); 0.01
Age at last visit in years	3.67 (1.42–11.09)	4.08 (2.00–11.50)	0.02 (−0.13 to 0.17); 0.82

All patients had myelomeningocele, were born 1997 through 2017, and were enrolled in the National Spina Bifida Patient Registry (NSBPR) 2009 through 2017. The significance of differences between cohorts in demographic characteristics was assessed by univariable Poisson regression. The significance of differences in frequencies of patients in categories of spinal segmental level of motor function was assessed by Poisson univariable regression, and the significance of differences in age at last visit recorded in the NSBPR was assessed by univariable Poisson linear regression. Percentages may not total 100% because of rounding. IRR, incidence rate ratio; CI, confidence interval.