Table 3. Baseline Characteristics Associated With Patient-Reported Regret at 5 Years After Diagnosis and Treatment for Localized Prostate Cancer.
| Characteristic | OR (95% CI) | P value |
|---|---|---|
| Baseline demographic characteristics | ||
| Age at diagnosis | 0.78 (0.62-0.97) | .03 |
| PDM-7 score | 0.80 (0.69-0.92) | .001 |
| Social support | 0.78 (0.67-0.90) | <.001 |
| Educational level | ||
| Some college or less | 1 [Reference] | NA |
| College graduate and above | 1.33 (0.98-1.79) | .06 |
| Married (vs not married) | 0.91 (0.63-1.31) | .60 |
| Black race (vs non-Black) | 0.87 (0.56-1.36) | .54 |
| Comorbidity, TIBI score | ||
| 0-2 | 1 [Reference] | NA |
| 3-4 | 1.33 (0.92-1.91) | .13 |
| ≥5 | 1.23 (0.80-1.90) | .34 |
| Tumor characteristics | ||
| D’Amico risk category | ||
| Low | 1 [Reference] | NA |
| Intermediate | 1.34 (0.97-1.85) | .08 |
| High | 1.5 (1.01-2.47) | .05 |
| Baseline patient-reported functional status | ||
| EPIC-26 | ||
| Sexual function | 1.12 (0.84-1.50) | .43 |
| Urinary incontinence | 0.99 (0.88-1.12) | .92 |
| Urinary irritative | 0.83 (0.66-1.05) | .12 |
| Bowel function | 0.96 (0.89-1.04) | .29 |
| Hormonal | 0.93 (0.76-1.15) | .51 |
| SF-36 | ||
| Physical functioning | 1.09 (0.96-1.20) | .19 |
| Emotional well-being | 0.80 (0.64-1.01) | .06 |
| Energy and fatigue | 0.90 (0.69-1.19) | .47 |
Abbreviations: EPIC-26, 26-item Expanded Prostate Index Composite; PDM-7, participatory decision-making tool; NA, not applicable; OR, odds ratio; SF-36, 36-Item Short Form Health Survey; TIBI, Total Illness Burden Index.