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Time evolution of mean lesion score of mice infected with HSV-1 (strain F) after pretreatment of mice with the polymer formulation alone (○ and ●), with polymer containing 5% SLS (▵ and ▴), or with polymer containing 1% DS (◊ and ⧫) for either 5 min (open symbols) or 1 h (filled symbols) prior to infection. Untreated infected mice were used as a control (□). Results are the mean of six animals per group.
