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Time evolution of mean lesion score and survival of mice infected intravaginally with HSV-2 (strain 333) after pretreatment of mice with pH 4.0 buffer (●), 1% SLS (×+), 5% SLS (▵), 1% DS (×), or 5% DS (◊) in buffer for 5 min prior to their intravaginal infection. Untreated infected mice were used as a control (○). Results are mean for eight animals per group.
