Table 2.
Therapy outcome after ALI/nivolumab.
| CT scan after cycle 2 | PET scan after cycle 2 | CT scan at EOT | PET scan at EOT | Allogeneic Stem-cell Transplant | Disease Status at Allogeneic SCT | Donor and Source of Allogeneic SCT | Disease and survival status at last FUP | |
|---|---|---|---|---|---|---|---|---|
| ALL PATIENTS (n=9) | PR: 3/9 PR CR: 6/9 CR | CR: 8/9 | CR: 8/9 | CR: 8/9 | NO: 5/9 | CR: 4/4 | Haploidentical BM: 2/4 | Alive and CR: 8/9 |
| YES: 4/9 | HLA identical sibling BM: 2/4 | |||||||
| Patient #1 | CR | CR | CR | CR | YES | CR | Haploidentical, BM | Alive and CR |
| Patient #2 | CR | CR | CR | CR | NO | – | – | Alive but relapsed |
| Patient #3 | CR | CR | CR | CR | NO | – | – | Alive and CR |
| Patient #4 | CR | CR | CR | CR | NO | – | – | Alive and CR |
| Patient #5 | PR | CR | CR | CR | YES | CR | HLA-identical sibling, BM | Alive and CR |
| Patient #6 | PR | CR | CR | CR | YES | CR | HLA-identical sibling, PB | Alive and CR |
| Patient #7 | PR | CR | CR | CR | YES | CR | Haploidentical, BM | Alive and CR |
| Patient #8 | CR | CR | CR | CR | NO | – | – | Alive and CR |
| Patient #9 | PR | PR | CR | CR | NO | – | – | Alive in CR |
CT: computed tomography; PET: positron emission tomography; EOT: end of treatment; SCT: stem cell transplantation; FUP: follow up; PR: partial remission, CR: complete remission, BM: bone marrow.