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. 2021 Nov 18;21:1243. doi: 10.1186/s12885-021-08927-w

Table 2.

Baseline patient characteristic: validation cohort

Variable M0 n (%) HEP n (%) PER n (%) HEP/PER n (%) p-value
Patients 47 51 44 28
Medium age (y) 66 65 67 61 0.55
Sex
 Female 20 (44.0) 24 (47.0) 23 (52.5) 13 (46.0) 0.36
 Male 27 (56.0) 27 (53.0) 21 (47.5) 15 (54.0)
Location of PT
 Right colon 15 (27.8) 15 (28.9) 17 (38.5) 9 (31.6) 0.80
 Left colon 32 (72.2) 36 (71.1) 27 (61.5) 17 (68.4)
UICC
 I 17 (36.0) 1 (2.9) 0 (0.0) 0 (0.0) 0.00011
 II 11 (23.5) 3 (5.9) 4 (9.0) 2 (7.1)
 III 19 (40.5) 6 (1.8) 14 (31.0) 4 (14.3)
 IV 0 41 (89.4) 26 (60.0) 22 (78.6)
Grading
 Low grade 29 (61.7) 29 (56.9) 22 (50.0) 17 (60.8) 0.70
 High grade 18 (38.3) 22 (44.1) 22 (50.0) 11 (39.2)
Time of liver metastases
 Synchron n.a. 41 (89.4) n.a. 22 (78.6) 0.5
 Metachron n.a. 10 (10.6) n.a. 6 (22.4)
Tumor perforation
 Yes 0 (0.0) 3 (5.9) 4 (9.1) 10 (35.7) 0.0002
 No 47 (100) 48 (94.1) 40 (90.9) 18 (64.3)

UICC union for international cancer control, T tumor size, N lymph node status, n.a. not applicable