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. 2021 Nov 18;21:399. doi: 10.1186/s12886-021-02152-6

Table 3.

Levels of cytokine (pg/mL, mean ± SD) in the aqueous humor in wet age-related macular degeneration patients

SRF (n = 9) PED (n = 8) SRT (n = 8)
(+) (−) P* (+) (−) P* (+) (−) P*
IL-1α 18.5 ± 15.9 216.3 ± 199.5 0.036 15.1 ± 9.7 170 ± 192.6 0.622 90.8 ± 152.1 17.9 ± 8.7 0.833
GM-CSF 19.9 ± 11.4 71.0 ± 67.4 0.050 18.5 ± 10.9 72.9 ± 65.6 0.006 48.1 ± 50.6 14.7 ± 13.4 0.065
IFN-γ 264.6 ± 62.6 676.6 ± 611.8 0.076 262.5 ± 63.2 681.4 ± 607.3 0.034 487.0 ± 451.5 238.4 ± 43.2 0.045
MCP-1 984.1 ± 255.7 854.4 ± 266.1 0.503 964.3 ± 228.3 899.1 ± 343.3 0.284 963.8 ± 287.6 913.0 ± 710.1 0.622
MIP-1α 812.8 ± 545.3 330.9 ± 127.6 0.076 787.4 ± 561.3 388.1 ± 190.6 0.065 506.3 ± 276.0 917.7 ± 710.1 0.284
MIP-1β 38.2 ± 29.1 21.3 ± 13.0 0.414 34.0 ± 29.2 30.7 ± 20.2 0.724 27.5 ± 17.4 41.9 ± 36.5 0.622
TNFα 860.0 ± 225.2 1973.3 ± 1399.3 0.106 836.4 ± 216.7 2026.6 ± 1343.3 0.011 1409.4 ± 1100.2 871.6 ± 295.3 0.284
VEGF 189.2 ± 73.6 349.3 ± 327.7 0.076 165.0 ± 57.6 403.8 ± 289.9 0.354 283.7 ± 232.8 166.0 ± 60.5 0.524

VEGF vascular endothelial growth factor

*Mann-Whitney U test