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. Author manuscript; available in PMC: 2021 Nov 19.
Published in final edited form as: J Equine Vet Sci. 2020 Dec 24;98:103364. doi: 10.1016/j.jevs.2020.103364

Fig. 1.

Fig. 1.

OCT4 expression during in vitro equine embryo development. OCT4 expression is designated in green with shade demonstrating the amount of protein expressed. Blue coloring represents weak or no OCT4 staining. OCT4 is expressed in the nucleus and cytoplasm of the immature oocyte, but after metaphase II, OCT4 expression restricts to the oocyte cytoplasm [12]. After fertilization, OCT4 continues to be expressed in the nucleus and the cytoplasm of the blastomeres until approximately the 6-cell stage. Expression of OCT4 then decreases until it reaches its lowest point at approximately the 40-cell stage [12].