Table 1.
Demographic data and biochemistry results in AL, ATTR, and control group
Variable | AL group (n=10), n (%) | ATTRwt group (n=15), n (%) | Control (n=10), n (%) |
---|---|---|---|
Demographic data | |||
Age (years) | 66.0±12.1# | 80.0±6.1† | 58.0±13.5 |
Gender male | 4 (40)# | 12 (80) | 5 (50) |
BSA (m2) | 1.68±0.17 | 1.81±0.14 | 1.80±0.10 |
SBP (mmHg) | 102.5±19.6 | 112.0±17.1 | 115.5±10.9 |
DBP (mmHg) | 63.5±11.3 | 68.0±11.3 | 68.5±11.5 |
Peripheral neuropathy | 3 (30) | 8 (53) | 0 |
Cardiovascular dysautonomia | 4 (40) | 7 (47) | 0 |
NYHA functional class | |||
I | 0 | 1 (6) | 10 (100) |
II | 4 (40) | 9 (60) | 0 |
III | 4 (40) | 5 (33) | 0 |
IV | 2 (20) | 0 | 0 |
Cardiac biomarkers | |||
cTnI (μg/L) | 0.46±0.43#,* | 0.09±0.07 | 0.01±0.01 |
NT-proBNP (pg/L) | 10817±15158* | 6272±6407 | 48±24 |
*AL groups versus all other groups; P<0.05, #AL group versus ATTR group; P<0.05, †ATTR group versus control group; P<0.05. ATTRwt=ATTR wild type, BSA=Body surface area, cTnI=Cardiac troponin I, DBP=Diastolic blood pressure, NT-pro-BNP=N-terminal prohormone of brain natriuretic peptide, NYHA=New York Heart Association, SBP=Systolic blood pressure