Table 2.
Global echocardiographic morphological and functional parameters in AL, ATTR wild type, and control group
| Variable | AL group (n=10) | ATTRwt group (n=15) | Control group (n=10) |
|---|---|---|---|
| Morphology | |||
| LVEDV (ml) | 63.3±44.7 | 80.1±28.3 | 99.2±23.9* |
| LVESV (ml) | 36.5±33.9 | 42.9±15.6 | 38.9±10.9 |
| LVEDd (mm) | 39.8±7.9 | 43.5±6.8 | 45.3±4.8 |
| LVESd (mm) | 27.8±9.4 | 31.3±4.8 | 28.2±5.4 |
| IVSd (mm) | 17.0±3.7 | 18.2±4.6 | 8.8±1.4*,# |
| PWd (mm) | 15.4±3.8 | 16.3±4.2 | 8.3±1.3*,# |
| RWT | 0.80±0.25 | 0.77±0.29 | 0.37±0.06*,# |
| ECC index | 1.11±1.10 | 1.13±0.22 | 1.06±0.06 |
| LVM index (g/m2) | 158.1±57.8 | 185.5±72.4 | 70.1±19.3*,# |
| LAD (mm) | 43.6±10.0† | 52.6±8.5 | 36.3±3.1*,# |
| LAV index (ml/m2) | 38.7±11.4† | 61.3±16.5 | 26.3±6.2*,# |
| Diastolic function | |||
| E wave (cm/s) | 95.2±29.1 | 90.3±23.6 | 79.1±14.9 |
| A wave (cm/s) | 53.6±24.7 | 54.0±31.3 | 56.2±9.6 |
| E/A ratio | 1.92±1.08 | 2.19±1.14 | 1.44±0.39 |
| DecT (ms) | 144.6±38.4 | 145.6±42.4 | 217.0±56.2*,# |
| E/E’ | 25.7±12.6 | 18.9±4.1 | 6.5±0.8*,# |
| Myocardial function | |||
| LVEF (%) | 46.2±8.9 | 46.9±8.8 | 61.1±2.3*,# |
| SV index (ml/m2) | 15.6±6.1 | 20.4±7.6 | 33.3±6.4*,# |
| MCF (%) | 11.0±4.7 | 12.6±5.0 | 51.5±9.2*,# |
*Control group versus AL group; P<0.05, #Control group versus ATTR group; P<0.05, †AL group versus ATTR group; P<0.05. DecT=Deceleration time, ECC=Eccentricity, IVSd=Interventricular septum diameter, LAD=Left atrium diameter, LAV=Left atrium volume, LVEDd=Left ventricle end-diastolic diameter, LVEDV=Left ventricle end-diastolic volume, LVEF=Left ventricle ejection fraction, LVESd=Left ventricle end-systolic diameter, LVESV=Left ventricle end-systolic volume, LVM=Left ventricle mass, MCF=Myocardial contraction fraction, PWd=Posterior wall diameter, RWT=Relative wall thickness, SV=Stroke volume, ATTRwt=ATTR wild type