Table 5.

Receiver-operating characteristics curve characteristics and cutoff points of nondeformation-based and deformation-based echocardiographic parameters for differential diagnosis of AL versus ATTR wild-type amyloidosis

Variable	AUC	P	Cutoff	95% CI	Sens (%)	Spec (%)
LVM index (g/m2)	0.59	0.44		0.36-0.82
RWT	0.57	0.56		0.32-0.82
ECC index	0.50	0.98		0.27-0.73
LVEF (%)	0.52	0.87		0.28-0.76
SV index (ml/m2)	0.69	0.11		0.47-0.91
MCF (%)	0.59	0.11		0.36-0.82
GLS (%)	0.60	0.12		0.37-0.83
EFSR (%)	0.59	0.12		0.36-0.82
RRSR	0.57	0.54		0.32-0.82
GWI (mmHg%)	0.61	0.34		0.37-0.86
GCW (mmHg%)	0.67	0.15		0.44-0.90
GWW (mmHg%)	0.68	0.13		0.46-0.90
GWE (%)	0.74	0.04	86.5	0.55-0.96	80.0	66.7

AUC=Area under the curve, CI=Confidence interval, ECC=Eccentricity, EFSR=Ejection fraction on strain ratio, GCW=Global constructive work, GLS=Global longitudinal strain, GWE=Global work efficiency, GWI=Global work index, GWW=Global wasted work, LVEF=Left ventricle ejection fraction, LVM=Left ventricle mass, MCF=Myocardial contraction fraction, RRSR=Relative regional strain ratio, RWT=Relative wall thickness, SAB=Septal apical-to-base ratio, Sens=Sensibility, Spec=Specificity, SV=Stroke volume