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. 2021 Nov 16;9:e12232. doi: 10.7717/peerj.12232

Figure 4. Overexpression of circRBM33 induces the extracellular matrix (ECM) degradation.

Figure 4

(A) The expression of circRBM33 in Ang II-induced vascular smooth muscle cells (VSMCs) was detected by RT-qPCR. (B) The expression of circRBM33 in Ang II-induced VSMCs with circRBM33 overexpression or control vector plasmids transfection was measured by RT-qPCR. (C) MMP-2, TIMP-1 expression in Ang II-treated VSMCs in each group was detected by western blot. Data are expressed as mean ± SD. *p < 0.05, **p < 0.01. Experiments were run in triplicate.