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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Resuscitation. 2021 Aug 20;167:209–217. doi: 10.1016/j.resuscitation.2021.08.023

Table 1:

Study characteristics

Study Enrollment period Location FiO2 groups Total eligible Total included, N (%) Total excluded as no HR available for the first two minutes after birth No bradycardia Transient bradycardia Prolonged bradycardia
Wang et al 2005-2007 United States 0.21 vs 1.0 37 27 (73%) 10 (27%) 14 5 8
Escrig et al 2005-2007 Spain 0.3 vs 0.9 42 42(100%) 0 (0%) 2 25 15
Vento et al 2007-2008 Spain 0.3 vs 0.9 78 78 (100%) 0 (0%) 18 2 58
Rabi et al 2005-2007 Canada 0.21 vs 1.0 26 24 (92%) 4 (8%) 7 4 13
Aguar et al 2010-2012 Spain 0.3 vs 0.6 60 60 (100%) 0 (0%) 14 24 22
Rook et al 2018-2012 Netherlands 0.3 vs 0.6 139 61 (44%) 78 (54%) 44 4 13
Kapadia et al 2010-2011 United states 0.21 vs 1.0 51 51 (100%) 0 (0%) 28 11 12
Oei et al 2009-2014 Australia Malaysia Qatar 0.21 vs 1.0 287 262 (91%) 25 (9%) 127 47 88
Total 720 605 (84%) 115 (16%) 254 122 229

No bradycardia: HR ≥ 100 bpm throughout the first 10 minutes. Transient bradycardia: HR below 100 bpm for < two minutes. Prolonged bradycardia: HR below 100 bpm for ≥ two minutes.