FIGURE 3.

Baclofen reduces voluntary alcohol drinking in a heterogeneous rat population. Systemic administration of baclofen (1 and 1.5 mg/kg, intraperitoneal) reduced voluntary alcohol (A) but not water intake (B) in the two‐bottle choice procedure in a population of 47 rats. The decrease in voluntary alcohol intake after baclofen administration was not driven by either the AAR (n = 23) or the AAS rats (n = 17), since both groups displayed similar reduction in alcohol (C) while maintaining constant water intake (D) when treated with baclofen. * p < 0.05 compared with saline treatment (0 mg/kg group). AAR: Adulteration‐Alternative reward Resistant rats; AAS: Adulteration‐Alternative reward Sensitive rats