Fig. 3.

Antagonists of excitatory amino acid (EAA) receptors bilaterally microinjected into the caudal ventral respiratory group (cVRG) caused within 10 min depressant effects on spontaneous rhythmic expiratory activity and on cough reflex responses induced by mechanical stimulation of the tracheobronchial tree. Stimulation periods marked by filled bars. Traces are phrenic integrated neurogram (Phr IN); phrenic neurogram (Phr N); abdominal integrated electromyographic activity (Abd IEMG); abdominal electromyographic activity (Abd EMG). Anaesthetized, spontaneously breathing rabbits. Modified from Bongianni et al. 2005.