. Author manuscript; available in PMC: 2021 Nov 19.

Published in final edited form as: J Pharm Pharm Sci. 2021;24:267–276. doi: 10.18433/jpps31832

Table 2.

Pharmacokinetic parameters of α-PVP corrected for dose after 0.56, 1, and 3 mg/kg (sc) administration of α-PVP in control and vaccinated rats. The time to maximum concentration at all three doses occurred at either the 5 or 30 min blood collection time point in both the control and vaccinated rats (see Figure 1).

Dose (mg/kig)	Treatment (N)	C_max (ng/mL)	AUC_inf (n•mm/mL)
0.56	Control (6)	134 ± 42	14184±3198
	Vaccine (6)	994 ± 487	135592±67270

1.0	Control (6)	135 ± 37	13634±3327
	Vaccine (6)	646 ± 181	100958 ±40732

3.0	Control (6)	77 ± 24	10904± 1500
	Vaccine (6)	372± 118	69467 ± 32932