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. 2021 Nov 19;23(6):969–978. doi: 10.1007/s10198-021-01408-8

Table 4.

Top 10 underlying conditions with risk association to COVID-19 mortality

Underlying conditions Insured person (statutory scheme) Hospitalisation Ventilation Death
Trisomies, behavioural and developmental disorders 439,231 2.09*** (1.59–2.75) 2.18* (1.03–4.61) 5.73*** (3.55–9.27)
Dementia and organic psychoorganic syndromes 362,189 2.23*** (1.98–2.51) 2.11*** (1.60–2.78) 5.54*** (4.57–6.72)
(Metastasised) malignant neoplasms 211,613 1.99*** (1.66–2.38) 1.60* (1.00–2.54) 3.85*** (2.80–5.29)
Haematological neoplasms 243,932 1.68*** (1.42–2.00) 2.40*** (1.69–3.41) 2.95*** (2.15–4.04)
Mental illnesses 1,576,220 1.70*** (1.51–1.92)

2.02***

(1.45 – 2.82)

2.86*** (2.16–3.79)
Severe kidney disease, dialysis 335,354 2.15*** (1.89–2.45) 2.37*** (1.80–3.14) 2.83*** (2.18–3.67)

HIV

Tuberculosis

Systemic mycoses

67,885 1.47 (0.96–2.26) 3.35*** (1.65–6.79) 2.62** (1.15–5.98)

Cirrhosis of the liver

Liver failure

184,728 1.23 (0.99–1.54) 1.36 (0.84–2.20) 2.32*** (1.62–3.33)
Infections with multi-resistant germs/opp. Pathogens 439,231 1.51*** (1.26–1.81) 1.79** (1.22–2.62) 2.26*** (1.65–3.10)
Severe neurological diseases 362,189 1.72*** (1.46–2.01) 1.45 (0.95–2.20) 2.16*** (1.58–2.94)

For the underlying condition definition used here, please refer to the allocation table published. The complete list of underlying conditions is available in the results table, which has also been published

*pr( >|z|) < 0.05; **pr( >|z|) < 0.025; ***pr( >|z|) < 0.001; alpha-95% confidence interval in parentheses