TABLE 1.

Characteristics of participants in the study cohort

Variable	Mean	SD	SEM	Min	Max	Median
Age (years)	68.01	10.95	0.51	27.00	94.00	69.00
BMI (kg/m2)	28.40	5.71	0.27	11.48	52.67	27.67
Ancestrya proportions
European (Iberians)	0.70	0.13	0.01	0.23	0.93	0.72
Native American	0.11	0.04	0.00	0.03	0.50	0.11
African (Yoruba)	0.19	0.13	0.01	0.03	0.72	0.15

Variable	n	%
Diabetes mellitus	260	54.85
Hypertension	397	83.75
Dyslipidemias	341	71.94
Smoking	64	13.50
MACEb	42	13.77
Myocardial infarctions (i.e., STEMI and NSTEMI)b	19	6.23
Stent thrombosisb	15	4.92
Strokes/TIAb	14	4.59
Deathsb	4	1.31
Bleedings eventsc	77	16.24
Aspirin users	300	63.29
Statins users	375	79.11
CCBs users	127	26.79
PPIs users	95	20.04
LVEF ≤40%	39	8.22
ACS and stable CAD	344	72.57
Coronary artery stentingd	177	37.34
Peripheral artery disease	114	24.05
Gender
Female	212	44.73
Male	262	55.27

Due to rounding errors, percentages may not equal 100%.

Abbreviations: ACS, acute coronary syndrome; BMI, body mass index; CAD, coronary artery disease; CCB, calcium channel blocker; LVEF, left ventricular ejection fraction; MACE, major adverse cardiovascular event; NSTEMI, non‐ST‐elevation myocardial infarction; PPI, proton pump inhibitor; STEMI, ST‐elevation myocardial infarction; TIA, transient ischemic attack.

^aAverage European, Native American and African ancestral genomic proportions at population level were estimated by ADMIXTURE software using the whole‐genome Infinium Multi‐Ethnic Hispanic AMR/AFR MEGA BeadChip array from Illumina.

^bMACE reports available only in a subset of 305 patients.

^cBleeding events is a combination of major and minor events.

^dAll patients with ACS and some with CAD underwent PCI (i.e., percutaneous coronary intervention) or coronary artery stenting.