TABLE 3.

Results for multivariate linear regression with different variables predicting PRU values in Caribbean Hispanics on clopidogrel

Variable	B	SE	95% CI	β	t	p value
(Intercept)	118.70	14.60	[89.90, 147.50]	0.00	8.13	<0.001
Diabetes	19.81	9.10	[1.86, 37.76]	0.15	2.18	0.031
Gender (M)	−17.87	8.63	[−34.88, −0.85]	−0.13	−2.07	0.040
African ancestry (YRI)	−68.54	34.27	[−136.11, −0.97]	−0.14	−2.00	0.047
rs662 carriers	19.37	9.41	[0.82, 37.92]	0.13	2.06	0.041
rs2032582 carriers	31.90	14.25	[3.79, 60.01]	0.15	2.24	0.026
rs12041331 carriers	−19.37	9.87	[−38.83, 0.09]	−0.14	−1.96	0.051
rs4244285 single carrier	40.54	11.05	[18.76, 62.33]	0.24	3.67	<0.001
rs4244285 double carrier	89.27	36.63	[17.03, 161.52]	0.16	2.44	0.016
African ancestry: rs12041331	−83.67	42.28	[−167.04, −0.30]	−0.19	−1.98	0.049

F(10,198) = 4.79, p < 0.001, R ² = 0.19.

Unstandardized Regression Equation: PRU = 118.70 + 19.81 * [Diabetes] − 17.87 * [Gender: males] − 68.54 * [African Ancestry status] + 19.37 * [rs662 carrier] + 31.90 * [rs2032582 carrier] − 19.37 * [rs12041331 carrier] + 40.54 * [rs4244285 single carrier] + 89.27 * [rs4244285 double carrier] − 83.67 * [African Ancestry: rs12041331 interaction].

Abbreviations: CI, confidence interval; PRU, P2Y12 reaction unit.