TABLE 1.
Drug groups and index drugs selected for studies in a rat model
| Class | Drug(s) |
|---|---|
| Atypical antipsychotic | Clozapine, Quetiapine, Risperidone |
| Benzodiazepine | Diazepam (positive control) |
| Imidazopyridine | Zolpidem |
| SARI | Trazodone |
| Skeletal muscle relaxant | Carisoprodol, Cyclobenzaprine |
| Tetracyclic antidepressant | Mirtazapine |
| Anticonvulsant | Topiramate |
| SSRI | Paroxetine |
| SNRI | Duloxetine |
| Melatonin receptor agonist | Ramelteon |
| Orexin receptor agonist | Suvorexant |
Abbreviations: SARI, serotonin receptor antagonist and reuptake inhibitor; SNRI, serotonin and norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor.