Table 2.

Likelihood of adherence with the clinical practice guideline on multivariable logistic regression.

Variable			Odds ratio for CPGa adherence (vs nonadherence)		95% CI		P value		C-statisticb
Model 1: Risk adjustment without initial labs (n=2406)
	ICUc admission within 48 hours	0.39		0.30-0.51		<.001		0.87
	ICU admission	0.53		0.42-0.69		<.001		0.87
	Required mechanical ventilation	1.18		0.79-1.77		.40		0.93
	All-cause in-hospital mortality	0.67		0.48-0.94		.02		0.88
	Composite outcomed	0.75		0.60-0.94		.01		0.82
	VTEe complication	0.87		0.65-1.17		.40		0.79
	Bleeding complication	0.39		0.21-0.73		.003		0.83
Model 2: Risk adjustment including initial labs (n=1181)
	ICU admission within 48 hours	0.28		0.19-0.43		<.001		0.90
	ICU admission	0.44		0.29-0.64		<.001		0.89
	Required mechanical ventilation	1.20		0.67-2.20		.50		0.94
	All-cause in-hospital mortality	0.92		0.56-1.52		.70		0.88
	Composite outcomed	0.61		0.42-0.87		.006		0.82
	VTE complication	1.05		0.64-1.71		.90		0.81
	Bleeding complication	0.47		0.17-1.26		.10		0.87

^aCPG: clinical practice guideline.

^bC-statistic or concordance statistic was calculated for each model.

^cICU: intensive care unit.

^dComposite outcome is defined as need for ICU admission, mechanical ventilation, all-cause in-hospital mortality, or hospital length of stay greater than 7 days.

^eVTE: venous thromboembolism.