Risk estimations for CV events (panel a), renal function decline (panel b) and diabetes disease progression based (panel c). The results are presented as Hazard ratios (HR) with 95% confidence interval (CI) of various endpoints in the validation dataset (n = 2347) estimated by Cox proportional hazard model, according to clusters and clustering methods: SIDD = severe insulin-deficient diabetes, SIRD = severe insulin-resistant diabetes, MOD = mild obesity-related diabetes, MARD = mild age-related diabetes, A-cluster = cluster-based subtyping following method proposed by Ahlqvist et al., SCORE = risk prediction based on Systematic COronary Risk Evaluation project, KDIGO = risk prediction based on Kidney Disease: Improving Global Outcomes project.