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. 2021 Nov 19;16(11):e0260169. doi: 10.1371/journal.pone.0260169

Table 2. Laboratory and imaging studies at the time of initial care among patients who survived and died, infected by SARS-CoV-2.

Characteristics Total Survivors Deceased p
n = 780 % n = 577 % n = 203 %
Laboratory studies, median (IQR)
Blood count
  Hemoglobin (g / dL) 14.4 (13.1–15.5) 14.6 (13.4–15.7) 13.8 (12.2–14.8) <0.001^
  Hematocrit (%) 42.6 (38.7–46.3) 43.2 (39.9–46.5) 40.6 (37.0–45.3) <0.001^
  Leukocytes (/ mm3) 8.840 (6.280–11.710) 8.155 (6.000–10.885) 9.980 (8.000–14.125) <0.001^
  Neutrophils (/ mm3) 6.870 (4.450–9.630) 6.235 (4.100–8.915) 8.650 (6.087–11.925) <0.001^
  Lymphocytes (/ mm3) 1.000 (730–1.400) 1.050 (792–1.500) 844 (600–1.240) <0.001^
  Platelets (mil / mm3) 248.0 (190.0–309.0) 254.0 (208.2–311.7) 225.0 (171.0–277.0) 0.001^
Renal function
  Creatinine (mg / dL) 0.9 (0.7–1.1) 0.9 (0.7–1.1) 1.1 (0.8–1.6) <0.001^
  Urea nitrogen (mg / dL) 16.2 (12.5–23.7) 15.3 (12.1–21.7) 24.4 (17.0–36.9) <0.001^
Liver function
  Total bilirubin (mg / dL) 0.57 (0.39–0.92) 0.52 (0.37–0.81) 0.65 (0.44–0.90) 0.008^
  Direct bilirubin (mg / dL) 0.31 (0.20–0.49) 0.26 (0.18–0.40) 0.40 (0.25–0.56) <0.001^
  Alanine aminotransferase (U / L) 43.4 (26.1–61.0) 38.8 (26.0–59.4) 42.9 (27.0–68.0) 0.377^
  Aspartate aminotransferase (U / L) 43.0 (29.6–61.0) 42.8 (28.2–61.0) 54.9 (33.0–85.0) 0.011^
  Lactic dehydrogenase (U / L) 367.0 (284.0–489.0) 359.0 (282.7–454.7) 458.0 (347.0–611.0) <0.001^
Others
  C-reactive protein (mg / L) 130.5 (63.6–206.4) 116.9 (49.4–186.1) 166.5 (105.7–257.5) <0.001^
  Ferritin (ng / mL) 1010.5 (451.0–1906.7) 899.0 (408.0–1657.4) 1340.0 (555.3–2000.0) 0.004^
  D-dimer (μg / mL) 340.0 (20.0–648.0) 299.5 (1.763–558.5) 497.0 (283.0–1141.0) <0.001^
  Troponin I (ng / mL) 0.008 (0.004–0.019) 0.007 (0.004–0.011) 0.024 (0.008–0.055) <0.001^
  Prothrombin time (sec) 13.9 (10.6–15.3) 12.9 (10.2–15.2) 14.1 (10.9–15.4) 0.023^
Imaging studies
Chest x-ray
  Abnormal findings 392 50.3 290 50.3 102 50.2 0.997
   Infiltrate 287 36.8 211 36.6 76 37.4 0.825
   Consolidation 94 12.1 67 11.6 27 13.3 0.525
   Groud-glass opacity 89 11.4 68 11.8 21 10.3 0.579
   Pleural effusion 26 3.3 18 3.1 8 3.9 0.575
   Atelectasis 23 2.9 18 3.1 5 2.5 0.634
   Air bronchogram 10 1.3 7 1.2 3 1.5 0.726*
Chest Computed Tomography
  Abnormal findings 395 50.6 276 47.8 119 58.6 0.008
   Groud-glass opacity 364 46.7 250 43.3 114 56.2 0.002
   Consolidation 118 15.1 91 15.8 27 13.3 0.398
   Air bronchogram 81 10.4 38 6.6 43 21.2 <0.001
   Atelectasis 45 5.8 31 5.4 14 6.9 0.423
   Lymphadenopathy 38 4.9 29 5.0 9 4.4 0.736
   Bronchiectasis 35 4.5 21 3.6 14 6.9 0.054
   Interlobular septal thickening 28 3.6 12 2.1 16 7.9 <0.001
   Pleural thickening 27 3.5 19 3.3 8 3.9 0.664

IQR: Interquartile range;

* Fisher’s exact test;

^ Mann-Whitney U Test