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. 2021 Nov 19;7(47):eabj0852. doi: 10.1126/sciadv.abj0852

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Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 5. — (A) Concentrations of HE4, CA-125, and YKL-40 were measured by enzyme-linked immunosorbent assay in uterine lavage samples. (B) Classification F1-scores for detection of the three biomarkers in lavage samples from training and test datasets, applying different protein concentration thresholds. (C) Classification F1-scores of nanosensor detection of each biomarker, applying different protein concentration thresholds. (D) The success of the detection of each biomarker via classification, applying different concentration thresholds. (E) Improvement in classification success, relative to the threshold of 100 pM.